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Drug ReportsSamarium sm-153 lexidronam
Samarium sm 153 lexidronam pentasodium
Quadramet (samarium sm 153 lexidronam pentasodium) is a small molecule pharmaceutical. Samarium sm 153 lexidronam pentasodium was first approved as Quadramet on 1997-03-28. It has been approved in Europe to treat neoplasms and pain.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
18 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
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Other
Total
Prostatic neoplasmsD011471C61313
Breast neoplasmsD001943EFO_0003869C5011
Neoplasm metastasisD009362EFO_000970811
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSamarium sm 153 lexidronam pentasodium
INN
Description
Samarium (153Sm) lexidronam (chemical name Samarium-153-ethylene diamine tetramethylene phosphonate, abbreviated Samarium-153 EDTMP, trade name Quadramet) is a chelated complex of a radioisotope of the element samarium with EDTMP. It is used to treat pain when cancer has spread to the bone.
Classification
Small molecule
Drug class
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Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID160369-78-8
RxCUI
ChEMBL IDCHEMBL2096660
ChEBI ID
PubChem CID9810246
DrugBank
UNII ID
Target
No data
Variants
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Financial
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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158 adverse events reported
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